UNAIR Avian Flu Research Center Invites Industrials and Government to Use New Technology

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“Vaccine Seeds Production Based on Cell Culture with Chip Technology Workshop” held in Laboratory of Bio Safety Level-2 Avian Influenza Research Center UNAIR, Wednesday, from September 28 to September 30. (Photo: Special)

UNAIR NEWS – The researchers of Avian Influenza Research Centre (AIRC) Universitas Airlangga invited ten people from the industrials, universities, and government to train them in making vaccine seeds with the latest technology. The activity called “Vaccine Seeds Production Based on Cell Culture with Chip Technology Workshop” held in Laboratory of Bio Safety Level-2 Avian Influenza Research Center UNAIR, Wednesday, from September 28 to September 30.

Dr. Reviany, Apt, of the committee of the workshop explained that the method of vaccine seeds production based on cell culture with chip technology was still rarely used, either in industrial laboratories, universities, and governments of Indonesia. So, from the laboratory aspect, AIRC was the first research center in Indonesia which produces vaccine seeds through cell culture with chip technology.

“It is a new system to produce vaccine seeds. In Indonesia, we use the conventional method, so we want to introduce new system which is more efficient to produce vaccine seeds,” said Reviany.

Generally, vaccine seeds production uses the method of embryonated chicken egg (TAB). There is a weakness of this TAB method, if the egg production is low, there will be no more medium used to replicate the virus. So, the cell culture can be used as an alternative.

The cell replication based on cell culture is developing. If the cell culture used a medium called flask, now we have chips technology. According to Reviany, production quota of vaccine seeds with CelCradle (vaccine seeds machine production) can be bigger than when using flask. Beside efficiency issue, the risk of contamination can be minimized.

Mesin celcradle yang digunakan untuk mengolah seed vaksin berbasis sel kultur dengan teknologi chip. (Foto: Istimewa)
Celcradle machine used to produce vaccine seeds based on culture cell with chip technology. (Photo: Special)

“So, if the general culture cell, flask is used. For example, one flask is filled with one milliliter.  During production we need a thousand milliliter. It means we need ten flasks. It is not efficient and the contamination risk is quite big, they’re difficult to handle as the flasks are quite big,” said the researcher of AIRC UNAIR.

Beside a workshop, the participants were briefed by experts. The experts were Prof. Dr. C. A. Nidom (senior researcher of AIRC), Dr. Neny Nuraini (PT. Bio Farma), Dr. Kamaluddin Zarkasie (PT. IPB Shigetta), and Revianny. Through the workshop, Reviany hoped that the participants can use the latest and upgraded technology to produce vaccine seeds. (*)

Author: Defrina Sukma S.
Editor : Dilan Salsabila

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